105101 / Anti-human CD22 Purified

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105101 / Anti-human CD22 Purified

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Anti-human CD22 Purified
Supplier Catalog Number105101
Product Size100?g
Long Description (4000 Characters)The clone MYG13 recognizes CD22 cell surface antigen. a 130-140kDa protein. The expression of CD22 is primarily restricted to the normal and neoplastic B cells but does not express on other haemopoietic cells. The initiation of expression of CD22 starts in the cytoplasm of pro-B and pre-B cells. Although CD22 is not expressed by plasma cells. it is abundantly expressed by the follicular mantle and marginal zone B-cells. Being a member of the immunoglobulin superfamily. CD22 serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and leukocytes. The role of CD22 in the activation of B-cells is primarily associated with tyrosine kinases mediated signal transduction pathways.
Entrez Gene ID933
Accession No.NC_000019.10 NC_018930.2 NT_011109.17
FormatPBS pH 7.2. 0.2% BSA (w/v). 0.09% sodium azide
Purity>95%
IsotypeIgG1.k
CloneMYG13
ImmunogenHuman Raji Cells
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